Medi-Weightloss is a physician-supervised medical weight loss franchise with over 100 locations nationwide. The clinically-backed program combines nutrition, pharmacological care including GLP-1s, IV therapy, and vitamin injections to help patients lose weight and keep it off — creating multiple recurring revenue streams for franchise owners.
At a Glance
Minimum Liquid Capital Required: $100,000 (Owner/Operator) or $250,000 (Semi-Absentee)
Ownership Model: Owner/Operator or Semi-Absentee
Location Type: Retail clinic (non-home-based)
Time Commitment: Full-time or Semi-Absentee
Experience Required: None; healthcare background helpful but not required
Top 5 Reasons to Invest
- $1,635,923 average sales across the system
- Multiple recurring revenue streams from weekly visits and products
- GLP-1 medications driving unprecedented demand
- Net Promoter Score of 88 (exceptional patient satisfaction)
- Two ownership paths: hands-on or semi-absentee
MEDI WEIGHTLOSS Franchise Opportunity
Medi-Weightloss was founded in 2005 and began franchising in 2008. The brand has grown to over 100 locations and helped patients lose more than 9.2 million pounds through its 3-phase, physician-supervised program.
The business addresses a massive market: 7 in 10 Americans are overweight or obese, and over 80% of consumers now consider wellness a top priority. Medi-Weightloss provides medically-supervised weight loss with individualized plans, pharmacological options including GLP-1 medications, IV therapy, vitamin injections, and signature supplements — services that drive recurring patient visits and multiple revenue streams.
Why Choose Medi-Weightloss®?
- $1,635,923 average sales with multiple recurring revenue streams from weekly visits, products, and services
- GLP-1 medications (Ozempic, Wegovy, etc.) creating unprecedented patient demand for medically-supervised weight loss
- Turnkey operation with web-based practice management, EMR, prescription labeling, and full HIPAA compliance
- Two ownership options — Owner/Operator for hands-on entrepreneurs or Semi-Absentee for investors
- Large protected territories with potential for healthcare provider, school, and corporate partnerships
ABF Exclusive Insights
Market Structure: The weight loss industry exceeds $3.7 billion with obesity affecting one-third of US adults. GLP-1 medications have transformed the category, driving patients to seek medically-supervised programs rather than DIY approaches.
Competitive Advantage: Unlike non-medical weight loss programs, Medi-Weightloss offers physician-supervised care with pharmacological options insurance may cover. The clinical credibility creates patient trust and retention that wellness-only competitors cannot match.
ABF Timing Insight: GLP-1 demand is reshaping weight loss. Patients want medical supervision for these medications, not just prescriptions. Medi-Weightloss is positioned to capture this wave with established clinical protocols and 17+ years of franchise infrastructure.
Training & Support
- Comprehensive hands-on training at corporate headquarters in Tampa, Florida
- Web-based practice management system with EMR, prescription labeling, and online ordering
- Ongoing support from operations, marketing, clinic management, and sales professionals
- Regional and national advertising plus customizable marketing materials (TV, radio, print, direct mail)
- Continuing education programs and on-site compliance visits
- Full HIPAA compliance systems and training
Franchise Owners That Thrive at Medi-Weightloss
- Entrepreneurial spirit with desire to own and grow a business
- Leadership abilities to motivate and manage small clinical teams (3-6 employees)
- Business acumen for data-driven decision-making in operations, sales, and marketing
- Strong people skills for building patient relationships and community connections
- Passion for health, wellness, and helping others achieve their goals
Franchise Fit & Capital Readiness
Who Is NOT A Good Fit for This Franchise
- Are you uncomfortable operating in a medical/clinical environment?
- Do you lack interest in health, wellness, or helping others improve their lives?
- Are you unable to meet staffing requirements (3-6 employees per location)?
- Are you inclined to modify clinical protocols rather than follow proven methods?
- Do you expect quick or guaranteed returns?
- Do you have less than $100,000 in liquid capital?
If you answered yes to any of these, this franchise may not be the right fit. Candidates who do not meet these criteria are typically not approved by the franchisor.
Ownership Options
Owner/Operator Path:
- Liquid Capital: $100,000
- Net Worth: $400,000
- Hands-on involvement in daily operations
Semi-Absentee Path:
- Liquid Capital: $250,000
- Net Worth: $750,000
- Manager-run with owner oversight
Investment Readiness Check
- Ownership timeline assessed during discovery process
- Credit and overall financial profile reviewed during approval
- Minimum Liquid Capital: $100,000 (Owner/Operator) or $250,000 (Semi-Absentee)
- Territory availability and clinic location assessed during validation
All financial thresholds are set by the franchisor and are non-negotiable during approval.
Franchisor Authority Disclosure
America’s Best Franchises provides guidance and introductions. Final approval criteria, financial thresholds, and territory decisions are determined exclusively by the franchisor.
Frequently Asked Questions
Q. How much liquid capital is required to qualify? A. $100,000 for Owner/Operator model or $250,000 for Semi-Absentee model, set by the franchisor.
Q. Do I need a medical background? A. No medical background required. Medi-Weightloss clinics employ physicians and medical professionals. Franchise owners focus on business operations, marketing, and patient experience.
Q. How many employees are needed? A. Typically 3-6 employees depending on clinic size, including medical staff.
Q. What services generate revenue? A. Multiple streams: weekly patient visits, GLP-1 and other medications, IV therapy, vitamin injections, signature supplements and products, and pharmacological care.
Q. Can I own multiple locations? A. Yes. Medi-Weightloss supports single-unit and multi-unit ownership with large protected territories.
Next Steps
Complete the form below to request a qualification review and discuss territory availability for Medi-Weightloss.
This profile represents general franchise information. Individual results may vary. Refer to the Franchise Disclosure Document for complete details.



